Articles

Zajets Ie.R., Demchenko V.F., Baranov Yu.S., Olszewski S.V. Methodological assurance of quality control of the new domestic fungicide GREENEX, SC and safety its applications on soybean and grapes

UDC: 613:632.95.028:633.491
DOI: 10.15407/zht2019.65.012

Zajets Ie.R., Demchenko V.F., Baranov Yu.S., Olszewski S.V.

METHODOLOGICAL ASSURANCE OF QUALITY CONTROL OF THE NEW DOMESTIC FUNGICIDE GREENEX, SC AND SAFETY ITS APPLICATIONS ON SOYBEAN AND GRAPES

A set of methods for the quality control of the new domestic mixed fungicide Greenex, SC produced by PE "Kemyline Agro" (Ukraine) and the safety of its use in agriculture has been developed for the first time. In these techniques modern methods of sample preparation, identification and quantitative definition of promokarb are applied: selective extraction, capillary gas-liquid chromatography with FID, TID and MS detection. Methods for determination the content of the active substance (propamocarb) in the preparation, as well as its residual amounts in the yield of target crops (grapes, soybeans) and processed products (grape juice, soybean oil) were used for state pre-registration tests, substantiation of hygienic standards and regulations, conditions for the safe use of fungicide Greenex, SC in agriculture.
Key words: Propamocarb, gas-liquid chromatography, mass-spectrometry, pesticides, fungicides, formulation of pesticides, pesticide residues.

REFERENCES

1. Natsionalna dopovid pro stan navkolyshnoho pryrodnoho seredovyshcha v Ukrayini u 2014 rotsi. Ministerstvo ekolohiyi ta pryrodnykh resursiv Ukrayiny. Kyyiv, 2016. 350 s.
2. EN 15662-2008. Foods of plant origin - Determination of pesticide residues using GC-MS and/or LC-MS/MS following acetonitrile extraction/partitioning and cleanup by dispersive SPE - QuEChERS-method.
3. Reasoned opinion on the review of the existing maximum residue levels (MRLs) for propamocarb according to Article 12 of Regulation (EC) No 396/2005. European Food Safety Authority. EFSA Journal. 2013. 11(4):3214. 72 p. https://doi.org/10.2903/j.efsa.2013.3214
4. Derzhavni sanitarni pravyla ta normy DSanPiN 8.8.1.2.3.4.- 000-2001. Dopustymi normy, kontsentratsiyi, kilkosti ta rivni vmistu pestytsydiv u silskohospodarskiy syrovyni, kharchovykh produktakh, povitri robochoyi zony, atmosfernomu povitri, vodi vodoymyshch, grunti. Ministerstvo okhorony zdorovʺya Ukrayiny, Holovne sanitarno-epidemiolohichne upravlinnya. Kyyiv, 2001. 244 s.
5. The Pesticide Manual: Twelfth Edition. Version 2.1. The British Crop Protection Council, London, 2001, 1190 p.
6. PPDB: Pesticide Properties Data Dfse. URL: http://sitem.herts.ac.uk/aeru/footprint/en/
7. Chunwei Wang, Yan Wang, Jie Gao, Yuncheng Xu, Lili Cui. Dissipation and residues determination of propamocarb in ginseng and soil by high-performance liquid chromatography coupled with tandem mass spectrometry. Environ Monit Assess. 2014. 186. 5327-5336, DOI 10.1007/s10661-014-3781-y https://doi.org/10.1007/s10661-014-3781-y
8. Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb: finalised 12 May 2006. EFSA Scientific Report. 2006. 78. 80 p, https://doi.org/10.2903/j.efsa.2006.78r
9. Guidelines on method validation to be performed in support of analytical methods for agrochemical formulations. CIPAC 3807.11 p. URL: https://cipac.org/images/pdf/validat.pdf
10. Manual on development and use of FAO and WHO specifications for pesticides: First edition - third revision. Pesticide specification. Rome. 2016. 306 p. URL: http://www.fao.org/3/a-i5713e.pdf
11. SANTE/11813/2017. Guidance document on analytical quality control and validation procedures for pesticide residues analysis in food and feed. 2017. 42 p. URL: https://ec.europa.eu/food/sites/food/files/plant/docs/pesticides_mrl_guidelines_wrkdoc_2017-11813.pdf
12. Pro vykorystannya norm tochnosti i pravylnosti vymiryuvan pry zdiysnenni kontrolyu za vmistom khimichnykh rechovyn v prodovolchiy syrovyni, produktakh kharchuvannya i obʺyektakh dovkillya i vidpovidnosti mizh velychynamy MDR i HDK ta hranytsyamy analitychnoho vyznachennya khimichnykh rechovyn: Postanova MOZ Ukrayiny vid 20.04.1999 r. No 20.
13. Tekhnichni Umovy. TU U 20.2-31052661-015:2018. HRINEKS - funhitsyd. PP «KEMYLAYN AHRO». 2018. 27 s.